Clinical Research & Scientific Publications
Explore BIOSerenity’s clinical research activities, scientific publications, conference abstracts, and medical posters in electrophysiology, neurology, cardiology, and sleep medicine.
Our research highlights ongoing advances in AI-powered diagnostics, connected healthcare technologies, and patient care innovation.
Leading Experts in Device Validation, Vast Real World Database. Our Large Brain Model and biomarkers lead to new discoveries in neurology.
If you have any questions, you can contact us here : clinical.team@bioserenity.com
AI Somno
Performance of BIOSERENITY AI SOMNO device in staging and scoring sleep studies automatically: a retrospective validation study
AI Normal/Anormal
BIOSERENITY AI Normal/Abnormal EEG algorithm performance: retrospective validation study
AI Seizure
Performance of BIOSERENITY AI SEIZURE EEG algorithm in detecting epileptic seizures in standard hospital EEGs and long-term home EEGs.
TeleEPI
TeleEPI – Integrated care pathway for people with epilepsy based on an unobtrusive AI-powered telemedical system
2026 – 2027
Centre Hospitalier Universitaire Vaudois, CHUV
Service d’Epileptologie
Département des Neurosciences Cliniques
Pr. Dr. med Philippe Ryvlin
A multimodal sleep foundation model for disease prediction
Rahul Thapa, Magnus Ruud Kjaer, Bryan He, Ian Covert, Hyatt Moore IV, Umaer Hanif, Gauri Ganjoo, M. Brandon Westover, Poul Jennum, Andreas Brink-Kjaer, Emmanuel Mignot & James Zou
January 2026 • Nature Medecine
The Clinical Impact of Periodic Limb Movements: Under-Recognition in
Sleep Disordered Breathing and Associations with Key Outcomes in
493,085 Patients
Yoel Green, Umaer Hanif, Katie Cederberg, Hyatt Moore, Ulysse Gimenez, Emmanuel Mignot
May 2025 • Sleep
Automatic detection of abnormal clinical EEG: comparison of a
finetuned foundation model with two deep learning models
Aurore Bussalb, François Le Gac, Guillaume Jubien, Mohamed Rahmouni, Ruggero G. Bettinardi, Pedro Marinho R. de Oliveira, Phillipe Derambure, Nicolas Gaspard, Jacques
Jonas, Louis Maillard, Laurent Vercueil, Hervé Vespignani, Philippe Laval, Laurent Koessler, Ulysse Gimenez
May 2025 • ArXiv (submitted)
BIOSerenity-E1: a self-supervised EEG model for medical applications
Ruggero G. Bettinardi†, Mohamed Rahmouni†,
Ulysse Gimenez (†contributed equally)
March 2025 • ArXiv (submitted)
A Multimodal Foundation Model Developed with 500K Hours of Sleep Recordings for Disease Predictions
Rahul Thapa, Magnus Ruud Kjær, Bryan He, Ian Covert, Hyatt Moore, Umaer Hanif, Gauri Ganjoo, M. Brandon Westover, Poul Jennum, Andreas Brink-Kjær, Emmanuel Mignot, James Zou
February 2025 • Sleep MedRxiv
The use of the Odds Ratio Product (ORP) and self-reported data to
detect comorbid insomnia and sleep apnea
Umaer Hanif, Veronica Guadagni, Kari Lambing, Ulysse Gimenez, Poul Jennum,
Alexander Sweetman, Vincent Mysliwiec
February 2025 • Sleep (submitted)
Associations between self-reported parasomnias and psychiatric illness in 370,000 patients with sleep disorders
Umaer Hanif, Alyssa Cairns, Vincent Mysliwiec, Ulysse Gimenez, Maxime Elbaz and Emmanuel Mignot
November 2024 • Psychiatry and Clinical Neurosciences
The PACIFIC ontology for heterogeneous data management in cardiology
Pierre-Yves Hervé, Marianne Allanic, Philippe Boutinaud, Jean-Joseph Christophe, Hüseyin Firat, Elie Mousseaux, Mathieu Pernot, Pierre Prot, Alfonso Sartorius-Carvajal, Frédérique Chézalviel-Guilbert, Jean-Sébastien Hulot
December 2023 • PubMed
Automatic Detection of Chronic Insomnia from Polysomnographic and Clinical Variables Using Machine Learning
Umaer Hanif, Ulysse Gimenez, Alyssa Cairns, Daniel Lewin, Nisar Ashraf, and Emmanuel Mignot
July 24-28 2023 • IEEE Engineering in Medicine and Biology Society (EMBC 2023) at the ICC Sydney, Australia
Interictal epileptiform discharges show distinct spatiotemporal and morphological patterns across wake and sleep
Amal Fouad, Hamed Azizollahi, Jean-Eudes Le Douget, François-Xavier Lejeune, Mario Valderrama, Liliana Mayor, Vincent Navarro and Michel Le Van Quyen
July 2022 • Brain Communications, 4(5)
Zero-crossing patterns reveal subtle epileptiform discharges in the scalp EEG
Jan Pyrzowski, Jean‑ Eudes Le Douget, Amal Fouad, Mariusz Siemiński, Joanna Jędrzejczak and Michel Le Van Quyen
February 2021 • Scientific Reports
EEG foundation models
Ulysse Gimenez
November 2025 • AWS Healthcare Day, Paris
Leveraging Self-Supervised EEG Foundation Models for Data-Efficient and Clinically Robust Neurological Diagnostics
Guillaume Jubien, Ruggero Bettinardi, Aurore Bussalb, Mohamed Rahmouni, Francois Le Gac, Ulysse Gimenez
November 2025 • AI for Health, Paris – Award of Best Scientific Abstract
Algorithmes de détection de micro-éveils de haute performance avec un modèle de deep learning
Mohamed Rahmouni, Aurore Bussalb, Maxime Elbaz, Guillaume Jubien, Ulysse Gimenez
November 2023 • Le congrès du Sommeil, Lille
Algorithmes de scoring de PSG innovants : co-coconstruction entre l’intelligence artificielle et l’expertise des professionnels
Guillaume Jubien, Gauthier Brisson, Aurore Bussalb, Marie-Lou Cartier, Louis Coroller, Maxime Elbaz, Méline Grégoire, Pedro Marinho, Hugo Tete, Ulysse Gimenez
November 2023 • Le congrès du Sommeil, Lille
Algorithme de haute performance de classification des états du sommeil chez l’enfant (6-18 ans)
Gautier Artru, Pedro Marinho, Guillaume Jubien, Maxime Elbaz, Aurore Guyon, Patricia Franco, Ulysse Gimenez
November 2024 • Le congrès du Sommeil, Lille
Identifier la COMISA à l’aide de biomarqueurs EEG et de résultats auto-déclarés
Umaer Hanif, Veronica Guadagni, Kari Lambing, Ulysse Gimenez, Poul Jennum, Alexander Sweetman, Magdy Younes, Vincent Mysliwiec
November 2024 • Le congrès du Sommeil, Lille
Performance of USleep Algorithm to a Better Than “Gold-Standard” Polysomnogram Validation Data Set
Umaer Hanif, Alyssa Cairns, Tammie Radke, Guillaume Jubien, Vincent Mysliwiec
2024 • SLEEP, 38th annual meeting of the APSS, Houston
BIOSerenity A.I.: The Development of Algorithms to Detect Seizures
Gray Cloe, Azizollahi Hamed, Le Douget Jean Eudes, Wahnoun Remy
2022 • American Epilepsy Society, Chicago
Associations entre les parasomnies et les paramètres de la polysomnographie
Umaer Hanif, Ulysse Gimenez, Alyssa Cairns, Daniel Lewin, Nisar Ashraf, and Emmanuel Mignot
November 2023 • Le congrès du Sommeil, Lille
